Prof. Charles H. Knowles

Queen Mary University of London School of Medicine NCBRSI

MECHANOTRANSDUCTION IN MOUSE VISCERAL AFFERENT FIBRES IS MODULATED BY VOLTAGE-GATED SODIUM CHANNEL SUBTYPE 1.9 (NAV1.9)
2013-01-01
English, Irritable Bowel Syndrome, Brain-gut and gut-brain axes, neuro-hormonal, neuralimmune and visceral sensitivity, Abstract, 2013
Glycogen metabolic enzymes in the gastrointestinal tract of mouse and man: Pathway defects cause neuromuscular pathology and explain symptoms in GINMD
2012-09-08
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Functional characterisation of human and mouse proximal colon as a site of nutrient sensing
2012-09-08
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Assessment and treatment of defecation disorders
2012-01-01
English, Syllabus contribution, 2012
A new classification for GI neuromuscular disorders
2012-09-07
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
P2Y mediated activation of mouse and human sensory nerves: Critical role for Nav1.9
2012-09-06
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Characterization of Transient Anal Sphincter Relaxations (TASRs) in health using high resolution anorectal manometry: Redefining the sampling reflex?
2012-09-08
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
The effect of psychophysiological autonomic modulation on human esophageal pain hypersensitivity
2012-09-08
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
The role of Nav1.9 in the activation of visceral afferent fibres by human inflammatory supernatants
2012-09-08
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Anxiety and sympathetic nervous system activation are associated with the development of human esophageal pain hypersensitivity
2012-09-07
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Mechanical and chemical stimulation of human visceral afferents
2012-09-07
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Prospective comparison of balloon expulsion, anorectal manometry and evacuation proctography for the diagnosis of evacuatory dysfunction
2012-09-07
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
Medium term outcomes following sacral nerve stimulation in patients with severe rectal evacuatory dysfunction allied to rectal hyposensitivity
2012-09-07
English, Abstract, European Society of Neurogastroenterology and Motility (ESNM), American Neurogastroenterology and Motility Society (ANMS), 2012
THE ROLE OF NAV 1.9 IN VISCERAL AFFERENT SIGNALLING
2011-10-25
English, Abstract, 2011
Assessment and treatment of defecation disorders
2012-01-01
English, Presentation, Clinical aspects, Medical management, Colon, Investigation and Diagnosis, Surgical management, Gastrointestinal motility, Rectum, Colonic and rectal conditions, GI Neuromuscular disease, 2012
Gastroparesis and pseudo-obstruction
2013-01-01
English, Presentation, Aetiology / Causes, Investigation and Diagnosis, Gastrointestinal motility, Stomach, Classification, Delayed gastric emptying, 2013
Optimising access to human tissue from surgery
2013-01-01
English, Presentation, Ethics and Publication, 2013
Working Party Report: Guidelines on histological techniques and reporting: The London Classification of GI neuromuscular pathology
2009-01-01
English, Presentation, Clinical aspects, Investigation and Diagnosis, Classification, Pathology, Management review, GI Neuromuscular disease, Neuromuscular disease, 2009
ADVANCED AGE LEADS TO REDUCED SENSITIVITY OF MOUSE INTESTINAL AFFERENT NEURONS TO BRADYKININ
2013-01-01
English, Irritable Bowel Syndrome, Brain-gut and gut-brain axes, neuro-hormonal, neuralimmune and visceral sensitivity, Abstract, 2013
Mechanical causes of anorectal outlet obstruction: Diagnostic and therapeutic strategy
2015-10-26
English, Presentation, 2015, Neurogastroenterology & Motility, Paediatrics, Primary Care, Radiology & Imaging
Surgical treatment
2016-10-18
English, Presentation, 2016, Neurogastroenterology & Motility, Paediatrics, Primary Care, Surgery, Young GI Track
Paediatric Intestinal Pseudo-obstruction: Evidence and Consensus-based Recommendations From an ESPGHAN-Led Expert Group

English, European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), Paediatrics, Small Intestine & Nutrition, Standards and Guidelines, 2018
Surgical management of constipation

English, Syllabus contribution, Postgraduate Teaching, 2019
Surgical management of constipation
2019-10-20
English, Presentation, 2019, Standards & Guidelines
Surgery
2019-10-22
English, Presentation, Chairman's Choice, Neurogastroenterology & Motility, Radiology & Imaging, Young GI Track, 2019, Standards & Guidelines, Nurses