Benign Focal Liver Lesions

The increasing use of novel imaging modalities is paralleling the growing discovery of focal liver lesions in otherwise asymptomatic patients. It is imperative that the pathological examination of incidentalomas is as accurate as possible to ensure correct diagnosis and adoption of treatment options.

This online course addresses the diagnosis and management of benign focal liver lesions and is based on presentations (with 89 accompanying slides) given by Deike Strobel, Minneke Coenraad, Marijn Sijtsma and Iris Nagtegaal as part of the “Incidentaloma | Focal liver lesion” session recorded in June 2015 at the United European Gastroenterology Summer School in Prague, Czech Republic. By using an evidence-based approach, the e-course tackles frequent findings, such as cysts, haemangiomas and focal nodular hyperplasia, as well as more rare findings, namely hepatocellular adenomas. Conventional and contrast-enhanced ultrasound are highlighted as playing a key role in the differential diagnosis of solid benign liver lesions. Several clinical cases, aimed at both young and experienced clinicians, are showcased to illustrate the diagnostic and management issues that may be encountered.

The combined video footage has a total duration of approximately 52 minutes. The estimated time needed to complete the course, including the final assessment, is 1 hour.

This course was developed by: UEG.

Learning Objectives / Educational needs

  • To become familiar with frequent and rare benign focal liver lesions
  • To be able to make an accurate diagnosis by following an appropriate diagnostic algorithm
  • To be able to clarify lesion identity (benign/malignant) on conventional and contrast-enhanced ultrasound
  • To be able to decide on appropriate clinical management following diagnosis
  • To get to know what needs to be considered in the case of liver cell adenoma—a rare liver lesion with a heterogeneous morphology


Rui Castro, The Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, Portugal

Leading authors

Deike Strobel, Consultant Gastroenterologist and Hepatologist; Senior Professor and Head of the Ultrasound Division, Department of Medicine I – Gastroenterology, Pneumology and Endocrinology, University Hospital Erlangen, Germany


Minneke Coenraad, Consultant Gastroenterologist, Department of Gastroenterology and Hepatology, Leiden University Medical Center, The Netherlands.

Marijn Sijtsma, Consultant Gastroenterologist, Department of Gastroenterology and Hepatology, Leiden University Medical Center, The Netherlands.

Iris Nagtegaal, Chair of Gastrointestinal Pathology, Department of Pathology, Radboud University Medical Center, The Netherlands. 

This course is suitable for all hepatologists, as well as radiologists, liver pathologists and any other healthcare professionals interested or involved in the diagnosis and management of focal liver lesions. 

  • The course is designed to last approximately 1 hour in total. 
  • All authors and the course editor have declared that they have no conflicts of interest in relation to the material in this course. 
  • The production of this course was funded entirely by UEG. No external sponsorship was received.
  • The material used in this course was prepared in 2015.
  • The name label on the speaker’s podium does not correctly identify Deike Strobel, the lead author and main presenter of this e-course. The name label is correct for the main video case presenter, Marijn Sijtsma.
  • Learners are invited to test their knowledge at the beginning and the end of the course via a series of 10 MCQs.
  • The course has a pass mark of 70%. Those scoring less than the required pass mark are encouraged to revisit the course and retake the assessment.

Release Date: 21 October 2015  / Accreditation Date: 28. January 2016