Liver Biopsy

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Despite its drawbacks, liver biopsy remains the gold standard for diagnosing several liver diseases. Furthermore, it may aid in choosing the best treatment or establishing disease prognosis. Clinicians should be able to accurately interpret clinical parameters justifying the need for liver biopsy, decide which procedure to use and be prepared to deal with complications.

This online course addresses the most relevant aspects of liver biopsy, from common indications and contraindications to management of complications. Emphasis is placed on practical elements, with the inclusion of hands-on demonstrations of the Menghini and Tru-Cut techniques. A clinical case provides a comprehensive example of how to interpret findings when deciding whether to perform liver biopsy. The course is based on presentations given by Joost Drenth, Helena Cortez-Pinto and Sofia Carvalhana recorded in June 2015 at the UEG Summer School in Prague, Czech Republic..

The combined video and audio footage has a total duration of approximately 50 minutes. The estimated time needed to complete the course, including the final assessment, is 1 hour.

This course was developed by: UEG.

  • To recognize the relevance of liver biopsy for the diagnosis of liver disease
  • To understand common indications and contraindications for liver biopsy
  • To become familiar with the different steps involved in performing a liver biopsy
  • To be able to decide on the most appropriate technique for performing liver biopsy, focusing on the Menghini and Tru-Cut biopsy devices
  • To be able to identify complications of liver biopsy and learn how to manage them

Rui Castro, The Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, Portugal

Leading authors:
Joost PH Drenth, Gastroenterologist, Professor and Head of the Department of Gastroenterology and Hepatology of the Radboud UMC, Nijmegen, The Netherlands.

Helena Cortez-Pinto, Associate Professor of Medicine, Faculty of Medicine of Lisbon; Hepatologist, Department of Gastroenterology, University Hospital of Santa Maria, Lisbon, Portugal.

Sofia Carvalhana, Hepatologist, Department of Gastroenterology, University Hospital of Santa Maria, Lisbon, Portugal.

This course is suitable for practicing hepatologists, as well as liver pathologists, nurses and any other healthcare professionals interested in, or actively performing, liver biopsies.

The course is designed to last approximately 1 hour in total. 

  • All authors and the course editor have declared that they have no conflicts of interest in relation to the material in this course. 
  • The production of this course was funded entirely by UEG. No external sponsorship was received.
  • The material used in this course was prepared in 2015.
  • The name label on the speaker’s podium does not correctly identify Helena Cortez-Pinto, the presenter of section 3. The name label is correct for the main video case presenter, Sofia Carvalhana (section 7).
  • Learners are invited to test their knowledge at the beginning and the end of the course via a series of 10 MCQs.
  • The course has a pass mark of 70%. Those scoring less than the required pass mark are encouraged to revisit the course and retake the assessment.

Release Date: April 2016

This course, made available on and organised by United European Gastroenterology, is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to award 1 European CME credit (ECMEC).
Each medical specialist should claim only those credits that he/she actually spent in the educational activity. The EACCME is an institution of the European Union of Medical Specialists (UEMS). Only those e-learning materials that are displayed on the UEMS-EACCME website have formally been accredited.